Invitrogen

SLIRP Recombinant Rabbit Monoclonal Antibody (3H18L4)

高级验证

This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.

查看其他7个SLIRP抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (2)
高级验证 (1)

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SLIRP Antibody (703099) in WB

Western blot analysis was performed on modified whole cell extracts (1% SDS) (30 µg lysates) of MCF7 (Lane 1), U-2 OS (Lane 2), MDA-MB-231 (Lane 3), T-47D (Lane 4), HCT 116 (Lane 5), LNCaP (Lane 6) and Hep G2 (Lane 7). The blot was probed with Anti-SLIRP Recombinant Rabbit Monoclonal Antibody (Product # 703099, 1:5,000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4,000 dilution). A ~12 kDa band corresponding to SLIRP was ... View More

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SLIRP Antibody — Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. MCF7 cells were transfected with SLIRP siRNA and decrease in signal intensity was observed in Western blot application using Anti-SLIRP Recombinant Rabbit Monoclonal Antibody (Product # 703099). {KD}

产品信息

703099

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:5,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

Expi293

分类

Recombinant Monoclonal

类型

Antibody

克隆号

3H18L4

抗原

Protein corresponding to human SLIRP [aa19- aa103]

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2762407

产品详细信息

This antibody is predicted to react with Monkey, Horse, Cat, Bovine.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

SLIRP (SRA stem-loop interacting RNA binding protein) is expressed in normal and tumor tissues, but the majority of the endogenous SLIRP resides in the mitochondria. SLIRP may regulate mitochondrial functions and has the potential to shut down estrogen in breast cancer cells and testosterone in prostate cancer cells. SLIRP has also been shown to turn down genes involved in energy metabolism.

仅用于科研。不用于诊断过程。未经明确授权不得转售。