Invitrogen

SLIT2 Polyclonal Antibody

查看其他8个SLIT2抗体

抗体检测数据 (1)

SLIT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SLIT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SLIT2 Antibody (PA5-142228) in IHC (P)

Immunohistochemistry (Paraffin) analysis of SLIT2 in paraffin embedded Human Spinal Cord using SLIT2 Polyclonal Antibody (Product # PA5-142228) at 4 µg/mL. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

SLIT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SLIT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis of SLIT2 in paraffin embedded Human Spinal Cord using SLIT2 Polyclonal Antibody (Product # PA5-142228) at 4 µg/mL. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.

产品信息

PA5-142228

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

4-8 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide with sequence DDCQDNKCKNGAH.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2932882

产品详细信息

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.

靶标信息

SLIT2 are ligands for Robo receptors and play a vital role for axonal migration/navigation during neural development. A number of cleavage products through alternate splicing are reported in the literature for SLIT2 proteins. The C-terminal cleavage proteins are more diffusible than the larger N-terminal protein that is more tightly cell associated. SLIT2 protein is expressed in tissues such as fetal lung, kidney, and adult spinal cord.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Slit homolog 2 protein; Slit-2

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基因别名: SLIL3; Slit-2; SLIT2

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UniProt ID: (Human) O94813

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Entrez Gene ID: (Human) 9353

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GTPase inhibitor activity calcium ion binding protein binding heparin binding identical protein binding protein homodimerization activity laminin-1 binding proteoglycan binding heparan sulfate proteoglycan binding Roundabout binding immunoglobulin superfamily cell adhesion molecule

参与通路

ureteric bud development negative regulation of protein phosphorylation cell migration involved in sprouting angiogenesis negative regulation of leukocyte chemotaxis axon guidance motor neuron axon guidance negative regulation of lamellipodium assembly negative regulation of endothelial cell migration negative regulation of smooth muscle cell migration spinal cord development chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration chemorepulsion involved in postnatal olfactory bulb interneuron migration corticospinal neuron axon guidance through spinal cord negative regulation of cell growth negative regulation of cell migration negative regulation of actin filament polymerization retinal ganglion cell axon guidance response to nutrient levels cellular response to hormone stimulus negative regulation of GTPase activity Roundabout signaling pathway positive regulation of apoptotic process negative regulation of vascular permeability branching morphogenesis of an epithelial tube axon extension involved in axon guidance negative regulation of inflammatory response positive regulation of axonogenesis negative chemotaxis induction of negative chemotaxis negative regulation of small GTPase mediated signal transduction response to cortisol apoptotic process involved in luteolysis negative regulation of chemokine-mediated signaling pathway cellular response to heparin negative regulation of smooth muscle cell chemotaxis negative regulation of mononuclear cell migration negative regulation of neutrophil chemotaxis negative regulation of monocyte chemotaxis negative regulation of retinal ganglion cell axon guidance negative regulation of cellular response to growth factor stimulus