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Immunogen sequence: LKSLIQIDLH DNPWDCTCDI VGMKLWVEQL KVGVLVDEVI CKAPKKFAET DMRSIKSELL CPDYSDVVVS TPTPSSIQVP ARTSAVTPAV RLNSTGAPAS LGAGGGASSV PL
SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: leucine rich repeat containing 11; Leucine-rich repeat-containing protein 11; SLIT and NTRK-like family, member 5; SLIT and NTRK-like protein 5; slit and trk like gene 5
基因别名: bA364G4.2; KIAA0918; LRRC11; SLITRK5
UniProt ID: (Human) O94991
Entrez Gene ID: (Human) 26050