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产品信息
PA5-20480
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 13 amino acid peptide from near the center of human Slitrk6.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11154498
产品详细信息
A suggested positive control is mouse lung tissue lysate.
PA5-20480 can be used with blocking peptide PEP-0600.
靶标信息
SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4832410J21Rik; neuronal transmembrane protein Slitrk6; RP11-272M24.2; SLIT and NTRK-like family, member 6; SLIT and NTRK-like protein 6; slit and trk like gene 6
基因别名: 4832410J21Rik; DFNMYP; SLITRK6; Sltk6
UniProt ID: (Human) Q9H5Y7, (Mouse) Q8C110
Entrez Gene ID: (Human) 84189, (Mouse) 239250, (Rat) 290467
startle response
lens development in camera-type eye
auditory receptor cell morphogenesis
axonogenesis
synapse assembly
visual perception
sensory perception of sound
adult locomotory behavior
vestibulocochlear nerve development
auditory behavior
multicellular organism growth
inner ear morphogenesis
camera-type eye development
neuron projection morphogenesis
response to stimulus
positive regulation of synapse assembly
vestibular reflex
linear vestibuloocular reflex
innervation
cochlea development
