Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: DNGRGMTSKQ LNNWAVYRLS KFTRQGDFES DHSGYVRPVP VPRSLNSDIS YFGVGGKQAV FFVGQSARMI SKPADSQDVH ELVLSKED
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SMC hinge domain-containing protein 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1
基因别名: KIAA0650; SMCHD1
UniProt ID: (Human) A6NHR9
Entrez Gene ID: (Human) 23347