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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SMC hinge domain-containing protein 1; structural maintenance of chromosomes flexible hinge domain containing 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1
基因别名: 4931400A14Rik; AW554188; KIAA0650; mKIAA0650; MommeD1; RGD1307234; SMCHD1
UniProt ID: (Human) Q9H6Q2, (Mouse) Q6P5D8
Entrez Gene ID: (Human) 23347, (Rat) 316732, (Mouse) 74355