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产品信息
PA5-96610
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1756-2005 of human SMCHD1 (NP_0561102)
偶联物
形式
Liquid
浓度
0.54 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808412
产品详细信息
Immunogen sequence: TTDAARRIYD ETQGRQQVLP LDSIYKKTLP DWKRSLPHFR NGKLYFKPIG DPVFARDLLT FPDNVEHCET VFGMLLGDTI ILDNLDAANH YRKEVVKITH CPTLLTRDGD RIRSNGKFGG LQNKAPPMDK LRGMVFGAPV PKQCLILGEQ IDLLQQYRSA VCKLDSVNKD LNSQLEYLRT PDMRKKKQEL DEHEKNLKLI EEKLGMTPIR KCNDSLRHSP KVETTDCPVP PKRMRREATR QNRIITKTDV; Positive Samples: HL-60, SKOV3, Jurkat, U-251MG, HepG2, Rat brain; Cellular Location: Chromosome
靶标信息
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SMC hinge domain-containing protein 1; structural maintenance of chromosomes flexible hinge domain containing 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1
基因别名: KIAA0650; RGD1307234; SMCHD1
UniProt ID: (Human) A6NHR9
Entrez Gene ID: (Human) 23347, (Rat) 316732
