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产品信息
PA5-66310
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2664957
产品详细信息
Immunogen sequence: HDKPVNAESQN SVGVFTREEV RNRIRNDPDD PEATKRLKLA MIQQYLKVES CESSSHSMDE VSLSAFGEWT EIPGAHHIIP SGFMRVVE
Highest antigen sequence identity to the following orthologs - mouse 94%, rat 93%.
靶标信息
Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates.
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生物信息学
蛋白别名: flavin containing amine oxidase; flavin-containing spermine oxidase; PAO-1; Polyamine oxidase 1; putative cyclin G1 interacting protein; Spermine oxidase
基因别名: C20orf16; PAO; PAO-1; PAO1; PAOH; PAOH1; SMO; SMOX; UNQ3039/PRO9854
UniProt ID: (Human) Q9NWM0
Entrez Gene ID: (Human) 54498
