Invitrogen

SMYD2 Polyclonal Antibody

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SMYD2 Antibody (PA5-30732) in WB

Western Blot using SMYD2 Polyclonal Antibody (Product # PA5-30732). Sample (30 µg of whole cell lysate). Lane A: Hela. Lane B: HCT116. 10% SDS PAGE. SMYD2 Polyclonal Antibody (Product # PA5-30732) diluted at 1:1,000.

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产品信息

PA5-30732

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

免疫沉淀 (IP)

1:100-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein fragment corresponding to a region within amino acids 115 and 310 of Human SMYD2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2548206

产品详细信息

Recommended positive controls: A549, HeLa, HepG2, HCT116.

Predicted reactivity: Human (99%), Mouse (94%), Rat (95%), Pig (98%), Chicken (88%), Bovine (97%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

SET domain-containing proteins, such as SMYD2, catalyze lysine methylation..

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Histone methyltransferase SMYD2; HSKM-B; Lysine N-methyltransferase 3C; N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2; zinc finger, MYND domain containing 14

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基因别名: HSKM-B; KMT3C; SMYD2; ZMYND14

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UniProt ID: (Human) Q9NRG4

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Entrez Gene ID: (Human) 56950

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功能

RNA polymerase II core binding p53 binding protein binding lysine N-methyltransferase activity protein-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity metal ion binding histone methyltransferase activity (H3-K36 specific) histone modifying enzyme

参与通路

negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated heart development negative regulation of cell proliferation histone H3-K36 methylation peptidyl-lysine monomethylation peptidyl-lysine dimethylation regulation of DNA damage response, signal transduction by p53 class mediator regulation of signal transduction by p53 class mediator