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SNX4 Antibody (PA5-52188) in IHC (P)
Immunohistochemical analysis of SNX4 in human cerebral cortex using SNX4 Polyclonal Antibody (Product # PA5-52188) shows strong nuclear positivity in neuronal cells.
产品信息
PA5-52188
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2647729
产品详细信息
Immunogen sequence: LRVRARVADR LYGVYKVHGN YGRVFSEWSA IEKEMGDGLQ SAGHHMDVYA SSIDDILEDE EHYADQLKEY LFYAEALRAV CRKHELMQYD LEMAAQDLAS KKQQCEELVT GTVRTFSLKG MTTKLFGQET PEQREARIKV LEEQINEGE
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 99%.
靶标信息
SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Sorting nexin-4
基因别名: 1810036H14Rik; AI037066; ATG24B; SNX4
UniProt ID: (Human) O95219, (Mouse) Q91YJ2
Entrez Gene ID: (Human) 8723, (Mouse) 69150, (Rat) 360725
