Invitrogen

SOD1 Polyclonal Antibody

高级验证

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

1个已发表图片

5 篇参考文献

查看其他55个SOD1抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 7

SOD1 Antibody (PA5-23245) in IHC (P)

Immunohistochemical analysis of SOD1 in formalin-fixed paraffin-embedded human liver tissue. Samples were incubated in SOD1 polyclonal antibody (Product # PA5-23245) using a dilution of 5 µg/mL. Isotype control (top) and this antibody (bottom).

Product Image Gallery

SOD1 Antibody — Altered expression of target protein upon cell treatment demonstrates antibody specificity. Western blot analysis of SOD1 using SOD1 Polyclonal Antibody (Product # PA5-23245) shows an increase in expression upon treatment with H2O2 in HEK-293 cells. {TM}

产品信息

PA5-23245

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.025-0.1 µg/mL

查看3篇已发表文章 3篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

5 µg/mL

酶联免疫吸附实验 (ELISA)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Mouse, Rat, Bovine, Human

已发表种属

Bovine, Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

superoxide dismutase enzyme from bovine erythrocytes

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.0 mg/mL

纯化类型

Protein A

保存液

PBS with 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2540770

靶标信息

SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Effects of BPA, BPS, and BPF on Oxidative Stress and Antioxidant Enzyme Expression in Bovine Oocytes and Spermatozoa.

Genes

Nguyen M,Sabry R,Davis OS,Favetta LA

PA5-23245 was used in Immunohistochemistry-immunofluorescence to support BPA's ability to alter oxidative stress in oocytes and, to a lesser extent, in sperm.

Fri Jan 14 00:00:00 EST 2022

Obesity is a risk factor for preoperative hypoxemia in Stanford A acute aortic dissection.

Medicine

Wu Z,Wang Z,Wu H,Hu R,Ren W,Hu Z,Chang J

PA5-23245 was used in an ELISA assay to investigate the roles of oxidative stress and inflammation in aortic lung dissection injuries within obesity using data collected from human patients.

Sun Mar 01 00:00:00 EST 2020

Remifentanil preconditioning protects against hypoxia-induced senescence and necroptosis in human cardiac myocytes in vitro.

Aging

Lewinska A,Adamczyk-Grochala J,Bloniarz D,Horeczy B,Zurek S,Kurowicki A,Woloszczuk-Gebicka B,Widenka K,Wnuk M

PA5-23245 was used in Western Blotting to investigate remifentanil preconditioning-based adaptive responses and underlying mechanisms using a model of human cardiomyocytes treated with the hypoxia-mimetic agent cobalt chloride.

Thu Jun 25 00:00:00 EDT 2020

Remifentanil preconditioning protects against hypoxia-induced senescence and necroptosis in human cardiac myocytes in vitro.

Aging

Lewinska A,Adamczyk-Grochala J,Bloniarz D,Horeczy B,Zurek S,Kurowicki A,Woloszczuk-Gebicka B,Widenka K,Wnuk M

Thu Jun 25 00:00:00 EDT 2020

Plant-Derived Molecules α-Boswellic Acid Acetate, Praeruptorin-A, and Salvianolic Acid-B Have Age-Related Differential Effects in Young and Senescent Human Fibroblasts In Vitro.

Molecules (Basel, Switzerland)

Lewinska A,Sodagam L,Bloniarz D,Siems K,Wnuk M,Rattan SIS

PA5-23245 was used in Western Blotting to report that young (25% replicative lifespan completed) and near-senescent (>90% replicative lifespan completed) human skin fibroblasts exposed for 1-15 days to a wide range of concentrations (0.1-100 µM) of the three selected phytochemicals, namely α-boswellic acid acetate (ABC), praeruptorin-A (PTA), and salvianolic acid-B (SAB) had age-related differential effects.

Sun Dec 29 00:00:00 EST 2019

Snake venoms promote stress-induced senescence in human fibroblasts.

Journal of cellular physiology

Lewinska A,Bocian A,Petrilla V,Adamczyk-Grochala J,Szymura K,Hendzel W,Kaleniuk E,Hus KK,Petrillova M,Wnuk M

PA5-23245 was used in Immunohistochemistry (Paraffin), Western Blot to investigate snake-venom-induced adaptive response at a relatively noncytotoxic concentration (0.01 µg/ml) in two human fibroblast cell lines of different origin, namely WI-38 fetal lung fibroblasts and BJ foreskin fibroblasts.

Wed May 01 00:00:00 EDT 2019

生物信息学

蛋白别名: Amyotrophic lateral sclerosis 1 (ALS1); Cu(2+)-Zn2+ superoxide dismutase; Cu-Zn superoxide dismutase; Cu/Zn SOD; Cu/Zn superoxide dismutase; epididymis secretory protein Li 44; HGNC:11179; hSod1; indophenoloxidase A; Indophenoloxidase A (IPOA); SOD, soluble; superoxide dismutase; Superoxide dismutase 1; Superoxide Dismutase 1 (SOD1); superoxide dismutase 1, soluble; Superoxide dismutase [Cu-Zn]; superoxide dismutase, cystolic

查看更多收起

基因别名: ALS; ALS1; B430204E11Rik; Cu/Zn-SOD; CuZnSOD; HEL-S-44; homodimer; hSod1; Ipo-1; Ipo1; IPOA; SOD; Sod-1; SOD1; SOD1L1; SODC