Invitrogen

SOD1 Recombinant Rabbit Monoclonal Antibody (HL2033)

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抗体检测数据 (8)

SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SOD1 Antibody (MA5-50364) in IHC (P)

Immunohistochemical analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) in Paraffin embedded mouse prostate tissue at a dilution of 1:100. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SOD1 Antibody in Western Blot (WB)

SOD1 Antibody in Western Blot (WB)

SOD1 Antibody in Western Blot (WB)

SOD1 Antibody in Western Blot (WB)

SOD1 Antibody in Western Blot (WB)

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SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) in Paraffin embedded mouse prostate tissue at a dilution of 1:100. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) in Paraffin embedded dog cerebellum tissue at a dilution of 1:100. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

SOD1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) in Paraffin embedded cat brain tissue at a dilution of 1:100. For Antigen retrieval citrate buffer, pH 6.0, as used for 15 min.

SOD1 Antibody in Western Blot (WB) — Western Blot analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) on 293T (30 μg), A431 (30 μg), HeLa (30 μg), and HepG2 (30 μg) whole cell extracts at a dilution of 1:5,000. Extracts were separated by 15% SDS-PAGE. An HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

SOD1 Antibody in Western Blot (WB) — Western Blot analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) in Mouse brain and Rat brain samples using a dilution of 1:1,000. Extracts were separated by 15% SDS-PAGE. An HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

SOD1 Antibody in Western Blot (WB) — Western Blot analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) in Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) using a dilution of 1:30,000. An HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

SOD1 Antibody in Western Blot (WB) — Western Blot analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) in MDCK whole cell extract (30 μg) using a dilution of 1:1,000. An HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

SOD1 Antibody in Western Blot (WB) — Western Blot analysis of SOD1 using SOD1 Recombinant Monoclonal Antibody (Product # MA5-50364) in Whole zebrafish (30 μg) using a dilution of 1:1,000. An HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

产品信息

MA5-50364

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

-

免疫组化（石蜡） (IHC (P))

1:100-1:1000

-

免疫细胞化学 (ICC/IF)

Assay-dependent

-

产品规格

种属反应

Dog, Cat, Human, Mouse, Rat, Zebrafish

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

HL2033

抗原

Recombinant fragmemt of human SOD1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_3094396

靶标信息

SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Amyotrophic lateral sclerosis 1 (ALS1); Cu(2+)-Zn2+ superoxide dismutase; Cu-Zn superoxide dismutase; Cu/Zn SOD; Cu/Zn superoxide dismutase; epididymis secretory protein Li 44; HGNC:11179; hSod1; indophenoloxidase A; Indophenoloxidase A (IPOA); sod(Cu/Zn); SOD, soluble; superoxide dismutase; Superoxide dismutase 1; Superoxide Dismutase 1 (SOD1); superoxide dismutase 1 soluble; superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)); Superoxide dismutase [Cu-Zn]; superoxide dismutase, cystolic

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基因别名: ALS; ALS1; B430204E11Rik; Cu/Zn-SOD; cuzn; CuZnSOD; HEL-S-44; homodimer; hSod1; Ipo-1; Ipo1; IPOA; SOD; Sod-1; SOD1; SODC; ZSOD

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UniProt ID: (Human) P00441, (Dog) Q8WNN6, (Mouse) P08228, (Rat) P07632, (Zebrafish) O73872

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Entrez Gene ID: (Human) 6647, (Dog) 403559, (Mouse) 20655, (Rat) 24786, (Zebrafish) 30553

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superoxide dismutase activity copper ion binding protein binding zinc ion binding protein phosphatase 2B binding identical protein binding protein homodimerization activity Rac GTPase binding chaperone binding antioxidant activity oxidoreductase activity enzyme binding metal ion binding oxidoreductase

参与通路

activation of MAPK activity response to reactive oxygen species response to superoxide ovarian follicle development positive regulation of cytokine production placenta development retina homeostasis response to amphetamine myeloid cell homeostasis platelet degranulation glutathione metabolic process superoxide metabolic process cellular iron ion homeostasis spermatogenesis embryo implantation cell aging sensory perception of sound locomotory behavior anterograde axonal transport retrograde axonal transport regulation of blood pressure response to heat response to organic substance transmission of nerve impulse removal of superoxide radicals response to nutrient levels peripheral nervous system myelin maintenance positive regulation of superoxide anion generation regulation of T cell differentiation in thymus response to carbon monoxide cellular response to potassium ion regulation of multicellular organism growth response to drug response to hydrogen peroxide superoxide anion generation positive regulation of apoptotic process positive regulation of catalytic activity regulation of GTPase activity negative regulation of neuron apoptotic process response to ethanol negative regulation of cholesterol biosynthetic process regulation of protein kinase activity regulation of organ growth response to antibiotic response to copper ion muscle cell cellular homeostasis thymus development response to axon injury hydrogen peroxide biosynthetic process regulation of mitochondrial membrane potential oxidation-reduction process heart contraction neurofilament cytoskeleton organization relaxation of vascular smooth muscle auditory receptor cell stereocilium organization cellular response to cadmium ion cellular response to ATP reactive oxygen species metabolic process response to antipsychotic drug positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway response to oxidative stress aging negative regulation of apoptotic process double-strand break repair apoptotic DNA fragmentation cellular response to oxidative stress response to xenobiotic stimulus response to metal ion response to methylmercury neuron cellular homeostasis