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Sequence homology: Cow: 100%; Goat: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 79%
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HMG box transcription factor SOX-14; Protein SOX-28; SRY (sex determining region Y)-box 14; Transcription factor SOX-14
基因别名: SOX14; SOX28
UniProt ID: (Human) O95416
Entrez Gene ID: (Human) 8403