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产品信息
PA5-110416
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-120 of human SOX5 (NP_6945341)
偶联物
形式
Liquid
浓度
1.12 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855827
产品详细信息
Immunogen sequence: MSSKRPASPY GEADGEVAMV TSRQKVEEEE SDGLPAFHLP LHVSFPNKPH SEEFQPVSLL TQETCGHRTP TSQHNTMEVD GNKVMSSFAP HNSSTSPQKA EEGGRQSGES LSSTALGTPE
靶标信息
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC35153; Sox5-BLM isoform; SRY (sex determining region Y)-box 5; SRY box 5; SRY-box containing gene 5; SRY-box containing gene 5-like 1; Transcription factor SOX-5
基因别名: A730017D01Rik; AI528773; L-SOX5; L-SOX5B; L-SOX5F; LAMSHF; Sox-5; SOX5; Sox5l1
UniProt ID: (Human) P35711, (Rat) F1M8W4, (Mouse) P35710
Entrez Gene ID: (Human) 6660, (Rat) 140587, (Mouse) 20678
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of chondrocyte differentiation
asymmetric neuroblast division
positive regulation of cartilage development
cellular response to transforming growth factor beta stimulus
positive regulation of mesenchymal stem cell differentiation
in utero embryonic development
central nervous system neuron differentiation
cell fate commitment
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
oligodendrocyte differentiation
cartilage development
regulation of timing of neuron differentiation
transcription, DNA-templated
