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This antibody detects endogenous protein at a molecular weight of 30 kDa.
Purity is >95% by SDS-PAGE.
SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 30000 Mr metaphase complex; Ovarian cancer-related protein; Spindlin-1; Spindlin1; SSEC P
基因别名: OCR; SPIN; SPIN1; TDRD24
UniProt ID: (Human) Q9Y657, (Mouse) Q61142, (Rat) Q4V8J7
Entrez Gene ID: (Human) 10927, (Mouse) 20729, (Rat) 361217