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产品信息
PA5-59274
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human SPIRE1. Recombinant protein control fragment (Product #RP-98283).
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2647868
产品详细信息
Immunogen sequence: LEEIKAERKL RPVSPEEIRR SRLDVTTPES TKNLVESSMV NGGLTSQTKE NGLSTSQQVP AQRKKLLRAP TLAELDSSES EEETLHK
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 83%.
靶标信息
Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein spire homolog 1; Spir-1; spire actin nucleation factor 1; spire family actin nucleation factor 1; spire homolog 1; spire-type actin nucleation factor 1; SPIRE1
基因别名: KIAA1135; Spir-1; SPIR1; SPIRE1
UniProt ID: (Human) Q08AE8
Entrez Gene ID: (Human) 56907
