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产品信息
PA5-103255
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SRPK3(Accession Q9UPE1), corresponding to amino acid residues G261-G311.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852618
产品详细信息
Antibody detects endogenous levels of total SRPK3.
靶标信息
STK23 (MSSK1), also known as SRPK3, is a muscle-specific member of the SRPKs. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MSSK-1; Muscle-specific serine kinase 1; muscle-specific serine kinase 1; MSSK1; serine arginine rich protein-specific kinase 3; serine/arginine-rich protein specific kinase 3; Serine/arginine-rich protein-specific kinase 3; serine/threonine kinase 23; serine/threonine kinase 23, muscle-specific serine kinase 1 70; Serine/threonine-protein kinase 23; serine/threonine-protein kinase SRPK3; SFRS protein kinase 3; SR-protein-specific kinase 3; SRSF protein kinase 3
基因别名: MSSK-1; MSSK1; SRPK3; STK23
UniProt ID: (Human) Q9UPE1, (Mouse) Q9Z0G2
Entrez Gene ID: (Human) 26576, (Rat) 293854, (Mouse) 56504
