Invitrogen

SRSF6 Polyclonal Antibody

高级验证

This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.

5个已发表图片

3 篇参考文献

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说明书

实验方案

技术支持

说明书

实验方案

技术支持

SRSF6 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 10

SRSF6 Antibody (PA5-41810) in ICC/IF

Immunofluorescence analysis of SRSF6 was performed using 70% confluent log phase SH-SY5Y cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with SRSF6 Polyclonal Antibody (Product # PA5-41810) at 5 µg/mL 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) for ... View More

SRSF6 Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

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SRSF6 Antibody — Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. T-47D cells were transfected with SRSF6 siRNA and reduction of signal was observed in Western Blot using SRSF6 Polyclonal Antibody (Product # PA5-41810). {KD}

产品信息

PA5-41810

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.2-1 µg/mL

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免疫细胞化学 (ICC/IF)

5 µg/mL

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产品规格

种属反应

Human

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human SFRS6

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2607949

产品详细信息

Peptide sequence: KERTNEGVIE FRSYSDMKRA LDKLDGTEIN GRNIRLIEDK PRTSHRRSYS

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 82%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

靶标信息

SFRS6 is involved in mRNA splicing and may play a role in the determination of alternative splicing. It belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Splicing factor SRSF6 mediates pleural fibrosis.

JCI insight

Liang LM,Xiong L,Cheng PP,Chen SJ,Feng X,Zhou YY,Niu Q,Wang M,Chen Q,Song LJ,Yu F,He XL,Xiang F,Wang X,Ye H,Ma WL

Published figure using SRSF6 polyclonal antibody (Product # PA5-41810) in Western Blot

Mon May 24 00:00:00 EDT 2021

Splicing factor SRSF6 mediates pleural fibrosis.

JCI insight

Liang LM,Xiong L,Cheng PP,Chen SJ,Feng X,Zhou YY,Niu Q,Wang M,Chen Q,Song LJ,Yu F,He XL,Xiang F,Wang X,Ye H,Ma WL

Published figure using SRSF6 polyclonal antibody (Product # PA5-41810) in Western Blot

Mon May 24 00:00:00 EDT 2021

Splicing factor SRSF6 mediates pleural fibrosis.

JCI insight

Liang LM,Xiong L,Cheng PP,Chen SJ,Feng X,Zhou YY,Niu Q,Wang M,Chen Q,Song LJ,Yu F,He XL,Xiang F,Wang X,Ye H,Ma WL

Published figure using SRSF6 polyclonal antibody (Product # PA5-41810) in Western Blot

Mon May 24 00:00:00 EDT 2021

The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression.

Molecular cell

Meyer C,Garzia A,Mazzola M,Gerstberger S,Molina H,Tuschl T

PA5-41810 was used in Western Blotting to study the role of TIA1 protein family in the mediated stress response and cell cycle progression.

Thu Feb 15 00:00:00 EST 2018

The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression.

Molecular cell

Meyer C,Garzia A,Mazzola M,Gerstberger S,Molina H,Tuschl T

PA5-41810 was used in Western Blotting to study the role of TIA1 protein family in the mediated stress response and cell cycle progression.

Thu Feb 15 00:00:00 EST 2018

生物信息学

蛋白别名: epididymis secretory protein Li 91; MGC5045; Pre-mRNA-splicing factor SRP55; Serine/arginine-rich splicing factor 6; Splicing factor, arginine/serine-rich 6; splicing factor, arginine/serine-rich, 55 kDa; SR splicing factor 6

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基因别名: B52; HEL-S-91; SFRS6; SRP55; SRSF6

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UniProt ID: (Human) Q13247

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Entrez Gene ID: (Human) 6431

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功能

nucleotide binding RNA binding protein binding pre-mRNA binding poly(A) RNA binding RNA splicing factor

参与通路