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ST6GAL1 Antibody (PA5-106647) in IHC (P)
Immunohistochemistry analysis of ST6GAL1 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with ST6GAL1 polyclonal antibody (Product # PA5-106647) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-106647
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ST6GAL1(Accession P15907), corresponding to amino acid residues K177-T227.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854315
产品详细信息
Antibody detects endogenous levels of total ST6GAL1.
靶标信息
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha 2,6-ST 1; B-cell antigen CD75; beta galactoside alpha 2,6 sialyltransferase 1; Beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; Sialyltransferase 1; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase); Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase); ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI
基因别名: AW742324; SIAT1; St6gal; St6Gal-I; ST6GAL1; ST6GalI; ST6N
UniProt ID: (Human) P15907, (Mouse) Q64685, (Rat) P13721
Entrez Gene ID: (Human) 6480, (Mouse) 20440, (Rat) 25197
N-acetylneuraminate metabolic process
humoral immune response
oligosaccharide metabolic process
O-glycan processing
protein N-linked glycosylation via asparagine
positive regulation of mononuclear cell proliferation
response to ethanol
negative regulation of chemotaxis
sialylation
regulation of substrate adhesion-dependent cell spreading
protein sialylation
negative regulation of macrophage apoptotic process
protein glycosylation
