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产品信息
PA5-117657
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human StAR-related lipid transfer protein 3 protein (170-445aa)
偶联物
形式
Liquid
浓度
0.61 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2902286
产品详细信息
This antibody has been tested in direct-ELISA
靶标信息
The steroidogenic acute regulatory (StAR) protein facilitates the movement of cholesterol from the outer to inner mitochondrial membrane in adrenal and gonadal cells, fostering steroid biosynthesis. MLN64 is a 445-amino acid protein of unknown function. When 218 amino-terminal residues of MLN64 are deleted, the resulting N-218 MLN64 has 37% amino acid identity with StAR and 50% of StAR's steroidogenic activity in transfected cells. Bacterially expressed N-218 MLN64 exerts StAR-like activity to promote the transfer of cholesterol from the outer to inner mitochondrial membrane in vitro. The presence of a protease-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN64 is similar to the organization of StAR. However, as MLN64 never enters the mitochondria, the protease-resistant domain of MLN64 cannot be a mitochondrial pause-transfer sequence, as has been proposed for StAR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Metastatic lymph node gene 64 protein; metastatic lymph node protein 64; MLN 64; Protein CAB1; StAR-related lipid transfer (START) domain containing 3; StAR-related lipid transfer domain containing 3; StAR-related lipid transfer protein 3; StARD3; START domain-containing protein 3; steroidogenic acute regulatory protein related
基因别名: CAB1; es64; MLN64; STARD3
UniProt ID: (Human) Q14849
Entrez Gene ID: (Human) 10948
