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产品信息
PA5-120359
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 165-464 of human STK38L (NP_055815.1).
偶联物
Unconjugated
形式
Liquid
浓度
1.86 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2913931
产品详细信息
Positive test controls include: HeLa, Mouse small intestine, Mouse brain, Rat stomach, Rat brain. The target is usually found in the following locations: Cytoplasm, Membrane, cytoskeleton.
Immunogen sequence: LIMEFLPGGD MMTLLMKKDT LTEEETQFYI SETVLAIDAI HQLGFIHRDI KPDNLLLDAK GHVKLSDFGL CTGLKKAHRT EFYRNLTHNP PSDFSFQNMN SKRKAETWKK NRRQLAYSTV GTPDYIAPEV FMQTGYNKLC DWWSLGVIMY EMLIGYPPFC SETPQETYRK VMNWKETLVF PPEVPISEKA KDLILRFCID SENRIGNSGV EEIKGHPFFE GVDWEHIRER PAAIPIEIKS IDDTSNFDDF PESDILQPVP NTTEPDYKSK DWVFLNYTYK RFEGLTQRGS IPTYMKAGKL
靶标信息
STK38L (also known as NDR2) or Nuclear Dbf2-related protein is a serine/threonine kinase in the subgroup of the AGC kinase family. STK38L act as novel pro-apoptotic kinase that is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis. STK38L is mainly involved in the regulation of structural processes in differentiating and mature neuronal cells and it is highly expressed with highest levels observed in the thymus. STK38L contains 12 protein kinase catalytic subdomains and a potential bipartite nuclear localization signal.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NDR2 protein kinase; nuclear Dbf2-related 2; Nuclear Dbf2-related kinase 2; serine/threonine kinase 38-like; Serine/threonine-protein kinase 38-like; STK38L
基因别名: 4930473A22Rik; B230328I19; KIAA0965; NDR2; Ndr54; RGD1564793; STK38L
UniProt ID: (Human) Q9Y2H1, (Mouse) Q7TSE6
Entrez Gene ID: (Human) 23012, (Mouse) 232533, (Rat) 691337
magnesium ion binding
actin binding
protein serine/threonine kinase activity
protein binding
ATP binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding
non-receptor serine/threonine protein kinase
