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STXBP1 Antibody (H00006812-D01P) in WB
Western Blot analysis of STXBP1 expression in transfected 293T cell line (H00006812-T03) by STXBP1 MaxPab polyclonal antibody.
Lane 1: STXBP1 transfected lysate(68.70 KDa).
Lane 2: Non-transfected lysate.
Lane 1: STXBP1 transfected lysate(68.70 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00006812-D01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
STXBP1 (NP_003156.1, 1 a.a. approximately 603 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MAPIGLKAVV GEKIMHDVIK KVKKKGEWKV LVVDQLSMRM LSSCCKMTDI MTEGITIVED INKRREPLPS LEAVYLITPS EKSVHSLISD FKDPPTAKYR AAHVFFTDSC PDALFNELVK SRAAKVIKTL TEINIAFLPY ESQVYSLDSA DSFQSFYSPH KAQMKNPILE RLAEQIATLC ATLKEYPAVR YRGEYKDNAL LAQLIQDKLD AYKADDPTMG EGPDKARSQL LILDRGFDPS SPVLHELTFQ AMSYDLLPIE NDVYKYETSG IGEARVKEVL LDEDDDLWIA LRHKHIAEVS QEVTRSLKDF SSSKRMNTGE KTTMRDLSQM LKKMPQYQKE LSKYSTHLHL AEDCMKHYQG TVDKLCRVEQ DLAMGTDAEG EKIKDPMRAI VPILLDANVS TYDKIRIILL YIFLKNGITE ENLNKLIQHA QIPPEDSEII TNMAHLGVPI VTDSTLRRRS KPERKERISE QTYQLSRWTP IIKDIMEDTI EDKLDTKHYP YISTRSSASF STTAVSARYG HWHKNKAPGE YRSGPRLIIF ILGGVSLNEM RCAYEVTQAN GKWEVLIGST HILTPTKFLM DLRHPDFRES SRVSFEDQAP TME
靶标信息
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EIEE4; FLJ37475; hUNC18; MGC146482; minisatellite 10g detected by probe MMS10; munc-18c; MUNC18-1; N-Sec1; neuronal SEC1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; rop; RP11-56D16.3; Syntaxin-binding protein 1; UNC-18 homolog; unc-18-1; Unc-18A; Unc18-1
基因别名: AI317162; AI326233; MMS10-G; Ms10g; Munc-18a; MUNC18-1; N-sec1; NSEC1; P67; Rb-sec1; RBSEC1; STXBP1; Sxtbp1; UNC18; Unc18-1; UNC18A; Unc18h
UniProt ID: (Human) P61764, (Mouse) O08599
Entrez Gene ID: (Human) 6812, (Mouse) 20910
platelet degranulation
vesicle docking involved in exocytosis
neurotransmitter secretion
neuromuscular synaptic transmission
axon target recognition
regulation of synaptic vesicle priming
glutamate secretion
protein transport
synaptic vesicle maturation
regulation of synaptic vesicle fusion to presynaptic membrane
negative regulation of synaptic transmission, GABAergic
regulation of SNARE complex assembly
negative regulation of neuron apoptotic process
positive regulation of calcium ion-dependent exocytosis
protein stabilization
long term synaptic depression
platelet aggregation
protein localization to plasma membrane
transport
exocytosis
vesicle-mediated transport
synaptic vesicle fusion to presynaptic active zone membrane
positive regulation of exocytosis
