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产品信息
H00006812-M01
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
6D1
抗原
STXBP1 (NP_003156, 74 a.a. approximately 168 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: VYLITPSEKS VHSLISDFKD PPTAKYRAAH VFFTDSCPDA LFNELVKSRA AKVIKTLTEI NIAFLPYESQ VYSLDSADSF QSFYSPHKAQ MKNPI
靶标信息
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EIEE4; FLJ37475; hUNC18; MGC146482; minisatellite 10g detected by probe MMS10; munc-18c; MUNC18-1; N-Sec1; neuronal SEC1; p67; Protein unc-18 homolog 1; Protein unc-18 homolog A; rop; RP11-56D16.3; Syntaxin-binding protein 1; UNC-18 homolog; unc-18-1; Unc-18A; Unc18-1
基因别名: AI317162; AI326233; MMS10-G; Ms10g; Munc-18a; MUNC18-1; N-sec1; NSEC1; P67; Rb-sec1; RBSEC1; STXBP1; Sxtbp1; UNC18; Unc18-1; UNC18A; Unc18h
UniProt ID: (Human) P61764, (Mouse) O08599
Entrez Gene ID: (Human) 6812, (Mouse) 20910
platelet degranulation
vesicle docking involved in exocytosis
neurotransmitter secretion
neuromuscular synaptic transmission
axon target recognition
regulation of synaptic vesicle priming
glutamate secretion
protein transport
synaptic vesicle maturation
regulation of synaptic vesicle fusion to presynaptic membrane
negative regulation of synaptic transmission, GABAergic
regulation of SNARE complex assembly
negative regulation of neuron apoptotic process
positive regulation of calcium ion-dependent exocytosis
protein stabilization
long term synaptic depression
platelet aggregation
protein localization to plasma membrane
transport
exocytosis
vesicle-mediated transport
synaptic vesicle fusion to presynaptic active zone membrane
positive regulation of exocytosis
