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Heparan sulfate 6-O-endosulfatases, such as Sulfatase 2, selectively remove 6-O-sulfate groups from heparan sulfate. Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Arylsulfatase; DKFZp313E091; Extracellular sulfatase Sulf-2; FLJ44488; FLJ90554; hSulf-2; MGC126411; mSulf-2; N-acetylglucosamine-6-sulfatase; OTTHUMP00000031223; RP5-1049G16.1; sulfatase FP2
基因别名: 2010004N24Rik; AU020235; HSULF-2; KIAA1247; mKIAA1247; MSulf-2; SULF2; UNQ559/PRO1120
UniProt ID: (Human) Q8IWU5, (Mouse) Q8CFG0
Entrez Gene ID: (Human) 55959, (Rat) 311642, (Mouse) 72043