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Invitrogen
SULT2A1 Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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SULT2A1 Antibody (PA5-12243) in WB
Western blot analysis was performed on whole cell extracts of HepG2 (Lane 1), MCF7 (Lane 2), tissue extracts of Mouse Liver (Lane 3) and Mouse Kidney (Lane 4). The blot was probed with SULT2A1 Polyclonal Antibody (Product # PA5-12243, 1:1000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 32kDa band corresponding to SULT2A1 was observed in HepG2 and Mouse Liver, but not in MCF7 and Mouse Kidney.
产品信息
PA5-12243
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 253-285 amino acids from the C-terminal region of human SULT2A
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Ammonium sulfate precipitation, Size-exclusion - Dialysis
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2302776
靶标信息
SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds. SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SULT2A1 plays a role in hepatic cholesterol homeostasis. SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sulphation of 3b-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SULT2B1b is expressed in prostate, skin, placenta and lung.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: alcohol/hydroxysteroid sulfotransferase; Bile salt sulfotransferase; bile-salt sulfotranasferase 2A1; Dehydroepiandrosterone sulfotransferase; DHEA-ST; HST; Hydroxysteroid Sulfotransferase; ST2; ST2A1; Sulfotransferase 2A1; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1; SULT2A3
基因别名: DHEA-ST; DHEAS; HST; hSTa; ST2; ST2A1; ST2A3; STD; SULT2A1
UniProt ID: (Human) Q06520
Entrez Gene ID: (Human) 6822
