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产品信息
75-298-FL594
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N323A/31
抗原
Fusion protein amino acids 1503-1545 of rat SUR2B (accession number Q63563-2) produced recombinantly in E. Coli.
偶联物
FL594
激发/发射光谱
594/615 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: VHTILTADLV IVMKRGNILE YDTPESLLAQ EDGVFASFVR ADM
靶标信息
Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2). The association of four Kir6.x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel. The primary function of the sulfonylurea receptor is to sense intracellular levels of the nucleotides ATP and ADP and in response facilitate the open or closing its associated Kir6.x potassium channel. Hence the KATP channel monitors the energy balance within the cell.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ABC36; ABC37; ATFB12; ATP-binding cassette sub-family C member 8; ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette transporter sub-family C member 9; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; CANTU; CMD1O; FLJ36852; HHF1; HI; HRINS; MRP8; PHHI; sulfonylurea receptor; Sulfonylurea receptor 1; Sulfonylurea receptor 2; sulfonylurea-binding protein 2; sulphonylurea receptor 1; SUR1delta2; TNDM2
基因别名: Abcc8; Abcc9; AI414027; AI449286; D930031B21Rik; Sur; SUR1; Sur2; SUR2A; SUR2B
UniProt ID: (Rat) Q09429, (Rat) Q63563, (Mouse) P70170
Entrez Gene ID: (Mouse) 20927, (Rat) 25559, (Rat) 25560, (Mouse) 20928
