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Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: PVAPKPPSRG LLDGLVNGAA SSAGIPEPPR LQGRGGELFA KRQSRADRYV VEGTPGPGLG PR
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.
SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Synaptopodin 2-like protein
基因别名: SYNPO2L
UniProt ID: (Human) Q9H987
Entrez Gene ID: (Human) 79933