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Stathmin 1 Antibody (PA5-20383) in IHC (P)
Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using Stathmin 1 Polyclonal Antibody (Product # PA5-20383) at 2.5 µg/mL. Tissue was fixed with formaldehyde and blocked with 0.1 serum for 1 h at RT; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody overnight at 4˚C. A goat anti-rabbit IgG H&L (HRP) at 1/250 was used as secon... View More
产品信息
PA5-20383
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 17 amino acid peptide from near the amino terminus of human op18.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11155369
产品详细信息
A suggested positive control is human brain tissue lysate.
PA5-20383 can be used with blocking peptide PEP-0500.
靶标信息
Stathmin 1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: leukemia associated phosphoprotein p18; leukemia-associated cytosolic phosphoprotein stathmin; Leukemia-associated gene protein; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; OTTHUMP00000008529; OTTHUMP00000008531; phosphoprotein 19; Phosphoprotein p19; pp17; pp19; Pr22 protein; Prosolin; Protein Pr22; RP1-125I3.5; Stathmin; stathmin 1 variant; stathmin 1/oncoprotein 18; STN1; testicular tissue protein Li 189; transmembrane protein C1orf215
基因别名: 19k; C1orf215; Lag; LAP18; OP18; P18; P19; Pig; PP17; Pp18; PP19; PR22; prosolin; SMN; STMN1
UniProt ID: (Human) P16949, (Rat) P13668, (Mouse) P54227
Entrez Gene ID: (Human) 3925, (Rat) 29332, (Mouse) 16765
microtubule depolymerization
mitotic spindle organization
axonogenesis
brain development
response to virus
regulation of microtubule polymerization or depolymerization
negative regulation of microtubule polymerization
neuron projection development
intracellular signal transduction
positive regulation of cellular component movement
regulation of cytoskeleton organization
mitotic cytokinesis
signal transduction
multicellular organism development
nervous system development
cell differentiation
