NeoBiotechnologies

Synaptophysin Monoclonal Antibody (SYP, 3551)

Synaptophysin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Synaptophysin Antibody (6855-MSM1-P1) in IHC (P)

Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human pancreatic carcinoma using Synaptophysin Monoclonal Antibody (Product # 6855-MSM1-P1).

Synaptophysin Antibody in Peptide array (ARRAY)

Synaptophysin Antibody in SDS-PAGE (SDS-PAGE)

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产品信息

6855-MSM1-P1

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

肽阵列 (Array)

Assay-dependent

产品规格

种属反应

Dog, Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

SYP, 3551

抗原

Recombinant fragment (around aa 224-313) of human Synaptophysin (SYP) protein

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

靶标信息

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.

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