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Syntenin 1 Antibody (PA5-28813) in IHC (P)
Syntenin 1 Polyclonal Antibody detects SDCBP protein at cytosol on mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. Syntenin 1 Polyclonal Antibody (Product # PA5-28813) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-28813
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Zebrafish
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human Syntenin 1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546289
产品详细信息
Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MDA-9; melanoma differentiation associated protein-9; Melanoma differentiation-associated protein 9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; Scaffold protein Pbp1; sdcbp; syndecan binding protein (syntenin); syndecan interacting protein; Syndecan-binding protein 1; syntenin; Syntenin-1; syntenin-b; TACIP18
基因别名: MDA-9; MDA9; sb:eu862; SDCBP; si:dkey-235k4.1; ST1; SYCL; syntenin-1; TACIP18
UniProt ID: (Human) B7ZLN2, (Mouse) O08992
Entrez Gene ID: (Human) 6386, (Mouse) 53378, (Zebrafish) 407719
glycoprotein binding
frizzled binding
interleukin-5 receptor binding
protein binding
protein C-terminus binding
cytoskeletal adaptor activity
growth factor binding
neurexin family protein binding
identical protein binding
protein homodimerization activity
syndecan binding
ephrin receptor binding
protein heterodimerization activity
protein N-terminus binding
cadherin binding involved in cell-cell adhesion
cell adhesion molecule binding
membrane trafficking regulatory protein
negative regulation of receptor internalization
protein targeting to membrane
substrate-dependent cell migration, cell extension
Ras protein signal transduction
chemical synaptic transmission
regulation of mitotic cell cycle
positive regulation of cell proliferation
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
actin cytoskeleton organization
positive regulation of cell growth
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
intracellular signal transduction
positive regulation of phosphorylation
positive regulation of JNK cascade
ephrin receptor signaling pathway
cell-cell adhesion
positive regulation of exosomal secretion
positive regulation of extracellular exosome assembly
