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产品信息
PA5-112957
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human TATA box-binding protein-associated factor RNA polymerase I subunit B protein (369-588AA)
偶联物
Unconjugated
形式
Liquid
浓度
0.44 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2867691
靶标信息
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during trancription initiation such as preinitiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RNA polymerase I-specific TBP-associated factor 63 kDa; SL1, 63kD subunit; TAFI63; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa; TATA box binding protein associated factor 1B; TATA box-binding protein-associated factor 1B; TATA box-binding protein-associated factor RNA polymerase I subunit B; TATA-box binding protein associated factor, RNA polymerase I, B; TBP-associated factor 1B; Transcription initiation factor SL1/TIF-IB subunit B
基因别名: MGC:9349; RAF1B; RAFI63; SL1; TAF1B; TAFI63
UniProt ID: (Human) Q53T94
Entrez Gene ID: (Human) 9014
RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
positive regulation of gene expression, epigenetic
