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This target displays homology in the following species: Guinea Pig: 82%; Mouse: 100%; Rat: 92%
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during trancription initiation such as preinitiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RNA polymerase I-specific TBP-associated factor 68 kDa; TAFI68; TATA box-binding protein-associated factor 1B; TATA box-binding protein-associated factor RNA polymerase I subunit B; TBP-associated factor 1B; TBP-associated factor RNA polymerase I 68; transcription factor TAFI68; Transcription initiation factor SL1/TIF-IB subunit B
基因别名: 4930408G01Rik; A230108M10Rik; p63; Taf1b; TAFI68; Tafi86
UniProt ID: (Mouse) P97358
Entrez Gene ID: (Mouse) 21340