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Predicted to react with Mouse and Rat samples.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bitter taste receptor T2R16; candidate taste receptor T2R4; candidate taste receptor T2R8; MGC163311; T2R16; T2R20; T2R4; T2R8; tas2r4 {ECO:0000250|UniProtKB:Q9JKT3}; taste receptor T2R8; Taste receptor type 2 member 108; Taste receptor type 2 member 20; Taste receptor type 2 member 4; Taste receptor type 2 member 8; taste receptor, type 2, member 4
基因别名: mGR08; mt2r8; T2R108; T2R16; T2r20; T2R4; T2r8; Tas2r108; TAS2R4; Tas2r8
UniProt ID: (Human) Q9NYW5, (Mouse) Q9JKT3, (Rat) Q67ET0
Entrez Gene ID: (Human) 50832, (Mouse) 57253, (Rat) 554302