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Invitrogen

TAX1BP1 Polyclonal Antibody

查看其他12个TAX1BP1抗体
说明书
实验方案
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说明书
实验方案
技术支持

产品信息

PA5-55076

应用
建议稀释比
已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200
-

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL
-
产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human TAX1BP1. Recombinant protein control fragment (Product #RP-101865).
查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2648242

产品详细信息

Immunogen sequence: ADAVAELKLN AMKKDQDKTD TLEHELRREV EDLKLRLQMA ADHYKEKFKE CQRLQKQINK LSDQSANNNN VFTKKTGNQQ KVNDASVNTD PATSASTVDV KPSPSAAEAD FDIVTKGQVC EMTKEIADKT EKYNK

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

靶标信息

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Tax1 (human T-cell leukemia virus type I) binding protein 1; Tax1-binding protein 1; TRAF6-binding protein

基因别名: CALCOCO3; PRO0105; T6BP; TAX1BP1; TXBP151

UniProt ID: (Human) Q86VP1

Entrez Gene ID: (Human) 8887

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