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Immunogen sequence: MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA; Positive Samples: OVCAR3, HeLa, 293T, U-87MG, Mouse testis; Cellular Location: Cytoplasm, cytoskeleton
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CFA; chaperonin cofactor A; co-chaperonin associated with a- & b-tubulin; cofactor A; TCP1-chaperonin cofactor A; tubulin cofactor a; Tubulin-folding cofactor A; Tubulin-specific chaperone A
基因别名: TBCA; Tbca13
UniProt ID: (Human) O75347, (Mouse) P48428, (Rat) Q6PEC1
Entrez Gene ID: (Human) 6902, (Mouse) 21371, (Rat) 366995
分子生物学功能: chaperonin