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Recommended positive controls: Neuro2A, GL261.
Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: T-box brain gene 1; T-box brain protein 1; T-box, brain, 1; T-box, brain, 1-like; T-brain-1; TBR-1; TES-56
基因别名: TBR-1; TBR1; TES-56
UniProt ID: (Human) Q16650, (Mouse) Q64336
Entrez Gene ID: (Human) 10716, (Mouse) 21375, (Rat) 680427