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Predicted to react with Mouse samples.
Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: TCEA-like protein 7; transcription elongation factor A (SII)-like 7; Transcription elongation factor A protein-like 7; Transcription elongation factor S-II protein-like 7
基因别名: 1110018P05Rik; MPMGp800C04260Q003; TCEAL7; WEX5
UniProt ID: (Human) Q9BRU2, (Mouse) A3KGA4
Entrez Gene ID: (Human) 56849, (Mouse) 100040972