Invitrogen

TCF21 Polyclonal Antibody

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TCF21 Antibody in Western Blot (WB)

TCF21 Antibody in Western Blot (WB)

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TCF21 Antibody (PA5-72640) in WB

Western blot analysis of TCF21 in zebra fish brain tissue lysates. Samples were incubated with TCF21 polyclonal antibody (Product # PA5-72640). Lysates: 35 µg/lane. DANRE tcf21 protein (arrow).

TCF21 Antibody in Western Blot (WB)

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TCF21 Antibody in Western Blot (WB) — Western blot analysis of TCF21 in zebra fish brain tissue lysates. Samples were incubated with TCF21 polyclonal antibody (Product # PA5-72640). Lysates: 35 µg/lane. DANRE tcf21 protein (arrow).

产品信息

PA5-72640

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

-

产品规格

种属反应

Zebrafish

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 5-35 amino acids from the N-terminal region of DANRE tcf21

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.4 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2718494

靶标信息

The basic helix-loop-helix transcription factor TCF21/Pod1 (also called capsulin or epicardin) is involved in kidney, lung and spleen organogenesis. It is also essential for normal development of the testes and ovaries. TCF21/Pod1 is involved in the transcriptional repression of steroidogenic factor 1 (Sf1/Nr5a1/Ad4BP), an orphan nuclear receptor that regulates the expression of multiple genes (including Scc) that mediate sexual differentiation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Capsulin; Epicardin; MyoRa2; TCF-21; Transcription factor 21

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基因别名: tcf21; zgc:123313

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UniProt ID: (Zebrafish) Q32PV5

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Entrez Gene ID: (Zebrafish) 558148

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RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding protein dimerization activity E-box binding basic helix-loop-helix transcription factor

参与通路

negative regulation of transcription from RNA polymerase II promoter branching involved in ureteric bud morphogenesis regulation of transcription from RNA polymerase II promoter skeletal muscle tissue development sex determination branchiomeric skeletal muscle development cell differentiation epithelial cell differentiation developmental process positive regulation of transcription from RNA polymerase II promoter spleen development embryonic digestive tract morphogenesis reproductive structure development gland development Sertoli cell differentiation palate development lung morphogenesis lung vasculature development bronchiole development negative regulation of androgen receptor signaling pathway artery development metanephric mesenchymal cell differentiation metanephric glomerular capillary formation