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TCP-1 delta Antibody (PA5-78954) in ICC/IF
Immunocytochemistry analysis of CCT4 using anti-CCT4 antibody (Product # PA5-78954) . CCT4 was detected in a section of U2OS cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 2μg/mL rabbit anti-CCT4 antibody (Product # PA5-78954) overnight at 4°C. DyLight®488 Conjugated Goat Anti-Rabbit IgG... View More
产品信息
PA5-78954
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human CCT4 recombinant protein (Position: R452-R539).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2746070
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A45; CCT-delta; Chaperonin containing T-complex polypeptide 1 subunit 4; chaperonin containing t-complex polypeptide 1, delta subunit; chaperonin containing TCP1, subunit 4 (delta); chaperonin subunit 4 (delta); Stimulator of TAR RNA-binding; T complex protein 1, delta; T-complex protein 1 subunit delta; TCP-1 delta; TCP-1-delta
基因别名: 2610204B21Rik; A45; C78323; CCT-DELTA; CCT4; CCTD; SRB
UniProt ID: (Human) F5H5W3, (Mouse) P80315, (Rat) Q7TPB1
Entrez Gene ID: (Human) 10575, (Mouse) 12464, (Rat) 29374
protein folding
binding of sperm to zona pellucida
positive regulation of telomere maintenance via telomerase
protein stabilization
positive regulation of telomerase activity
scaRNA localization to Cajal body
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
chaperone mediated protein folding requiring cofactor
