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Antibody detects endogenous levels of total CCT3.
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.
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蛋白别名: CCT-gamma; Chaperonin containing T-complex polypeptide 1 subunit 3; chaperonin containing TCP1, subunit 3 (gamma); chaperonin subunit 3 (gamma); hTRiC5; Matricin; mTRiC-P5; OTTHUMP00000025735; T-complex protein 1 subunit gamma; T-complex protein 1, gamma subunit; TCP-1-gamma; TCP1 (t-complex-1) ring complex, polypeptide 5
基因别名: AL024092; CCT-gamma; CCT3; CCTG; PIG48; TCP-1-gamma; Tcp1-rs3; TriC-P5; TRIC5
UniProt ID: (Human) P49368, (Mouse) P80318, (Rat) Q6P502
Entrez Gene ID: (Human) 7203, (Mouse) 12462, (Rat) 295230