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TCP1 epsilon Antibody (PA5-78955) in ICC/IF
Immunocytochemistry analysis of CCT5 using anti-CCT5 antibody (Product # PA5-78955) . CCT5 was detected in a section of U2OS cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum and then incubated with 2μg/mL rabbit anti-CCT5 antibody (Product # PA5-78955) overnight at 4°C. DyLight®488 Conjugated Goat Anti-Rabbit IgG... View More
产品信息
PA5-78955
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived human CCT5 recombinant protein (Position: L443-K535).
偶联物
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.01mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2746071
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human MCF-7 whole cell, human SiHa whole cell, human A549 whole cell, human 293T whole cell, human CACO-2 whole cell, human PC-3 whole cell, human U20S whole cell, rat testis tissue, mouse testis tissue, mouse liver tissue. IHC: mouse ovary tissue, rat ovary tissue, human intestinal cancer tissue. ICC/IF: U20S cell, LOVO Cell. Flow: A431 cell.
靶标信息
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CCT-epsilon; Chaperonin containing T-complex polypeptide 1 subunit 5; chaperonin containing TCP1, subunit 5 (epsilon); chaperonin subunit 5 (epsilon); epididymis secretory protein Li 69; T-complex protein 1 subunit epsilon; TCP-1-epsilon
基因别名: CCT-epsilon; CCT5; CCTE; HEL-S-69; KIAA0098; mKIAA0098; PNAS-102; TCP-1-epsilon; TCPE
UniProt ID: (Human) P48643, (Mouse) P80316, (Rat) Q68FQ0
Entrez Gene ID: (Human) 22948, (Mouse) 12465, (Rat) 294864
protein folding
binding of sperm to zona pellucida
response to virus
positive regulation of telomere maintenance via telomerase
protein stabilization
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
