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产品信息
H00200424-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TET3 (AAH22243.1, 859 a.a. - 1795 a.a.) partial human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEERYGEKGK AIRIEKVIYT GKEGKSSRGC PIAKWVIRRH TLEEKLLCLV RHRAGHHCQN AVIVILILAW EGIPRSLGDT LYQELTDTLR KYGNPTSRRC GLNDDRTCAC QGKDPNTCGA SFSFGCSWSM YFNGCKYARS KTPRKFRLAG DNPKEEEVLR KSFQDLATEV APLYKRLAPQ AYQNQVTNEE IAIDCRLGLK EGRPFAGVTA CMDFCAHAHK DQHNLYNGCT VVCTLTKEDN RCVGKIPEDE QLHVLPLYKM ANTDEFGSEE NQNAKVGSGA IQVLTAFPRE VRRLPEPAKS CRQRQLEARK AAAEKKKIQK EKLSTPEKIK QEALELAGIT SDPGLSLKGG LSQQGLKPSL KVEPQNHFSS FKYSGNAVVE SYSVLGNCRP SDPYSMNSVY SYHSYYAQPS LTSVNGFHSK YALPSFSYYG FPSSNPVFPS QFLGPGAWGH SGSSGSFEKK PDLHALHNSL SPAYGGAEFA ELPSQAVPTD AHHPTPHHQQ PAYPGPKEYL LPKAPLLHSV SRDPSPFAQS SNCYNRSIKQ EPVDPLTQAE PVPRDAGKMG KTPLSEVSQN GGPSHLWGQY SGGPSMSPKR TNGVGGSWGV FSSGESPAIV PDKLSSFGAS CLAPSHFTDG QWGLFPGEGQ QAASHSGGRL RGKPWSPCKF GNSTSALAGP SLTEKPWALG AGDFNSALKG SPGFQDKLWN PMKGEEGRIP AAGASQLDRA WQSFGLPLGS SEKLFGALKS EEKLWDPFSL EEGPAEEPPS KGAVKEEKGG GGAEEEEEEL WSDSEHNFLD ENIGGVAVAP AHGSILIECA RRELHATTPL KKPNRCHPTR ISLVFYQHKN LNQPNHGLAL WEAKMKQLAE RARARQEEAA RLGLGQQEAK LYGKKRKWGG TVVAEPQQKE KKGVVPTRQA LAVPTDSAVT VSSYAYTKVT GPYSRWI
靶标信息
TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; tet oncogene family member 3
基因别名: hCG_40738; KIAA0401; TET3
UniProt ID: (Human) O43151
Entrez Gene ID: (Human) 200424
