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Sequence of this protein is as follows: DPYSHVNDPY SLNPLHQPQQ HPWGQRQRQE VGSEAGSLLP QPRAALPQLS GLDPRRDYHS VRRPDVLLHS AHHGLDAGMG DSLSLHGLGH PGMEDVQSVE DANNSGMNLL
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: activating enhancer binding protein 2 beta; Activating enhancer-binding protein 2-beta; AP2-beta; transcription factor AP-2 beta (activating enhancer binding protein 2 beta); Transcription factor AP-2-beta
基因别名: AP-2B; AP2-B; TFAP2B
UniProt ID: (Human) Q92481
Entrez Gene ID: (Human) 7021