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Peptide sequence: YSMSDVLALP IFKQEESSLP PDNENKILPF QYVLCAATSP AVKLHDETLT
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%
This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-globin transcription factor CP2; Late SV40 factor; LBP 1C; SAA3 enhancer factor; Transcription factor LSF
基因别名: LBP1C; LSF; LSF1D; SEF; TFCP2; TFCP2C
UniProt ID: (Human) Q12800
Entrez Gene ID: (Human) 7024