Invitrogen

TGF beta-3 Polyclonal Antibody

TGF beta-3 Antibody in Western Blot (WB)

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TGF beta-3 Antibody (PA5-85307) in WB

TGF beta-3 Polyclonal Antibody detects TGF beta 3 protein by western blot analysis. Non-transfected (-) and TGF beta 3-transfected (+) 293T whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with TGF beta-3 Polyclonal Antibody (Product # PA5-85307) diluted at 1:5,000.

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产品信息

PA5-85307

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:10,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein encompassing a sequence within the center region of human TGF-beta-3.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.86 mg/mL

纯化类型

Antigen affinity chromatography

保存液

0.1M tris glycine, pH 7, with 10% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2792449

产品详细信息

Keep as concentrated solution.

Predicted reactivity: Mouse (97%), Rat (97%), Pig (87%), Chicken (86%), Rhesus Monkey (100%), Bovine (85%).

Positive Control: mouse placenta, human TGFB3-transfected 293T.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Transforming growth factor beta 3 (TGF beta 3) is the third member of the transforming growth factor family of cytokines, which also includes TGF beta 1 and beta 2. These cytokines are secreted in precursor form consisting of a bioactive C-terminal domain attached to an N-terminal domain known as latency associated protein (LAP). Cleavage of LAP results in the mature protein, which functions as a disulfide-linked homodimer. As with all members of the family, TGF beta 3 is highly conserved across species, with mouse and human TGF beta 3 demonstrating 100% sequence homology and cross-species activity.The members of this family can be expressed by most cell types and exert pleiotropic effects, which include the suppression of B- and T-cell effector activity, mediation of tissue healing, and suppression of tumor proliferation. The promotion of CD4+CD25+ T-cell expansion is a newly discovered function of the TGF beta cytokines, and indicates an important role in the protection against autoimmunity.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: FLJ16571; H-TGF-b-3; prepro-transforming growth factor beta-3; tgf beta 3; TGF-beta-3; Transforming growth factor; transforming growth factor beta-3; Transforming growth factor beta-3 proprotein; transforming growth factor, beta 3

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基因别名: ARVD; ARVD1; LDS5; RNHF; TGF-beta3; Tgfb-3; TGFB3

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UniProt ID: (Human) P10600

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Entrez Gene ID: (Human) 7043, (Mouse) 21809

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