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TMBIM1 Antibody (PA5-101938) in ICC/IF
Immunocytochemistry analysis of TMBIM1 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with TMBIM1 polyclonal antibody (Product # PA5-101938) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-101938
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TMBIM1(Accession Q969X1), corresponding to amino acid residues M251-T301.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851370
产品详细信息
Antibody detects endogenous levels of total TMBIM1.
靶标信息
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein lifeguard 3; Protein RECS1; Protein RECS1 homolog; Responsive to centrifugal force and shear stress gene 1 protein; Transmembrane BAX inhibitor motif-containing protein 1
基因别名: 2310061B02Rik; AA960455; AU024746; C78899; LFG3; mKIAA4161; MST100; MSTP100; PP1201; PSEC0158; RECS1; Tmbib1; TMBIM1
UniProt ID: (Human) Q969X1, (Mouse) Q8BJZ3
Entrez Gene ID: (Human) 64114, (Mouse) 69660, (Rat) 316516
negative regulation of catalytic activity
negative regulation of establishment of protein localization to plasma membrane
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of Fas signaling pathway
positive regulation of blood vessel remodeling
