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TMEM106B (extracellular) Antibody (ANR-177-200UL) in IHC (F)
Expression of TMEM106B in mouse hippocampus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-TMEM106B (extracellular) Antibody (#ANR-177) (1:600), followed by goat anti-rabbit-AlexaFluor-488. A. Staining in the hippocampal dentate gyrus region, showed TMEM106B immunoreactivity (green) in neurons (arrows). B. Pre-incubation of the antibody with TMEM106B (extracellular) B... View More
产品信息
ANR-177-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide EVIKELQEFYKDTYQK, corresponding to amino acid residues 114-129 of mouse CD9. Extracellular, 2nd loop.
偶联物
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: EVIKELQEFYKDTYQK
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Transmembrane protein 106B
基因别名: 2310036D22Rik; 5830455K21Rik; 6430519M21Rik; AI428776; AI661344; LRRGT00101; TMEM106B
UniProt ID: (Human) Q9NUM4, (Mouse) Q80X71, (Rat) Q6AYA5
Entrez Gene ID: (Human) 54664, (Mouse) 71900, (Rat) 312132
