Invitrogen

TMPRSS2 Polyclonal Antibody

TMPRSS2 Antibody in Immunocytochemistry (ICC/IF)

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TMPRSS2 Antibody (PA5-143839) in ICC/IF

Immunofluorescent analysis of TMPRSS2 in 4% paraformaldehyde-fixed A549 cells. Samples were incubated in TMPRSS2 Polyclonal antibody (Product # PA5-143839) using a dilution of 20 µg/mL followed by goat anti-rabbit IgG secondary antibody at a 1:500 dilution (green) and DAPI staining (blue).

TMPRSS2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

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产品信息

PA5-143839

应用

建议稀释比

已发表文章

免疫印迹 (WB)

2 µg/mL

免疫组织化学（多聚甲醛固定） (IHC (PFA))

20 µg/mL

免疫细胞化学 (ICC/IF)

20 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A peptide corresponding to 13 amino acids near the center of human TMPRSS2. The immunogen is located within amino acids 320-370 of TMPRSS2.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

4° C

运输条件

Wet ice

RRID

AB_3075053

产品详细信息

Predicted species reactivity based on immunogen sequence: Horse (100%); Rabbit (100%); Monkey (100%); Sheep (100%); Gorilla (100%); Cat (100%).

靶标信息

TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.

仅用于科研。不用于诊断过程。未经明确授权不得转售。