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Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Marmoset (100%); Gorilla, Orangutan (95%); Dog, Horse (89%); Hamster, Elephant, Panda, Pig (84%).
Antigen retrieval with HIER and sodium citrate at pH 6.0 is required for Immunohistochemistry using formalin-fixed paraffin-embedded human tissues.
This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAPH2; Channel-activating protease 2; Membrane-type serine protease 2; MT-SP2; Transmembrane protease serine 4; transmembrane serine protease 3; type II membrane serine protease
基因别名: CAPH2; MT-SP2; TMPRSS3; TMPRSS4; UNQ776/PRO1570
UniProt ID: (Human) Q9NRS4
Entrez Gene ID: (Human) 56649
分子生物学功能: serine protease