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This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate and dihydroxy-acetone phosphate in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: epididymis secretory protein Li 49; Methylglyoxal synthase; MGC88108; TIM; Triose-phosphate isomerase; Triosephosphate isomerase
基因别名: AI255506; HEL-S-49; TIM; TPI; Tpi-1; TPI1; TPID
UniProt ID: (Human) P60174, (Mouse) P17751
Entrez Gene ID: (Human) 7167, (Mouse) 21991